How does ATP drive glucose phosphorylation?

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Multiple Choice

How does ATP drive glucose phosphorylation?

ATP drives glucose phosphorylation by coupling the addition of a phosphate to glucose with the energy released when ATP is hydrolyzed. A kinase transfers the gamma-phosphate from ATP to glucose, yielding glucose-6-phosphate and ADP. The high energy released from ATP hydrolysis makes this otherwise unfavorable phosphorylation proceed, effectively “paying” the cost to activate glucose for metabolism. This energy-coupling idea is what makes the process work, rather than phosphorylation occurring spontaneously or being inhibited by ATP hydrolysis.

ATP drives glucose phosphorylation by coupling the addition of a phosphate to glucose with the energy released when ATP is hydrolyzed. A kinase transfers the gamma-phosphate from ATP to glucose, yielding glucose-6-phosphate and ADP. The high energy released from ATP hydrolysis makes this otherwise unfavorable phosphorylation proceed, effectively “paying” the cost to activate glucose for metabolism. This energy-coupling idea is what makes the process work, rather than phosphorylation occurring spontaneously or being inhibited by ATP hydrolysis.

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